Improving care for cohesinopathies: from heart phenotypes to novel therapies

改善粘连病的护理：从心脏表型到新疗法

• 批准号: 332057
• 负责人: Andelfinger Gregor U
• 金额: $ 23.68万
• 依托单位: Centre hospitalier universitaire Sainte-Justine (Montral, Qubec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-06-01 至 2018-06-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=332057&lang=en
• 关键词: Animal Models Facility; Cardiology; Cardiovascular Disease; Cohesinopathies; Development And Therapeutic Interventions; In Vitro Pathophysiology Study; Pre- Clinical Drug Development; Proteomics; Stem Cells; Transcriptomics

When cells in the body grow and take decisions such as how fast they divide or which fate they choose for their development, they need to read and interpret the genetic code. This process is facilitated by proteins that are called the cohesin complex. Whe

当体内的细胞生长并决定它们分裂的速度或它们选择何种命运进行发育时，它们需要阅读和解释遗传密码。这一过程是由一种叫做粘着蛋白复合物的蛋白质促进的。Whe