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Role of shugoshin-like 1 (SGOL1) in heart development

Role of shugoshin-like 1 (SGOL1) in heart development
Shugoshin-like 1 (SGOL1) 在心脏发育中的作用
批准号:
346002
负责人:
Andelfinger Gregor U
金额:
$70.45万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2021-03-01

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英文摘要
We have recently discovered a previously unknown disease in which both the heart and the gut progressively lose their pacemakers. We can show that this defect is due to a mutation in a gene called SGOL1 and we now suspect that SGOL1 is a novel master gene
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Weinstein Cardiovascular Development Conference 2020
Improving care for cohesinopathies: from heart phenotypes to novel therapies
Genetic and functional dissection of a novel pacemaking syndrome: a model for SGOL1 mutations
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