Exploring the Development of Biologically-Weighted Multi-Pollutant Exposure Surfaces for the Evaluation of Air Pollution Health Effects

探索开发生物加权多污染物暴露表面以评估空气污染对健康的影响

• 批准号: 478516-2015
• 负责人: Hatzopoulou, Marianne
• 金额: $ 6.61万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Collaborative Health Research Projects
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=579574
• 关键词: Exploring; Development; Biologically; Weighted; Multi

Population-based studies of the health effects of air pollution increasingly rely on exposure surfaces to assign exposures to large numbers of study participants. Such surfaces are available for a growing list of air pollutants through satellite technology and other models; however, evaluating the integrated health effects of multi-pollutant exposures remains a challenge. To address this need, we propose the development of biologically weighted multi-pollutant exposure surfaces that combine multiple air pollutants and health effects. For example, relevant mechanisms for cardiovascular health may include changes in blood pressure. Through this approach, a single surface is developed that reflects the expected impact of air pollution mixtures on specific physiological effects across a given geographical area. We also aim to integrate these surfaces within a transportation model allowing us to capture the traffic-related air pollution and health effects of transport policy scenarios at a metropolitan scale.

基于人群的空气污染对健康影响的研究越来越多地依赖于暴露表面来分配暴露 大量的研究参与者。这样的表面可以通过卫星对越来越多的空气污染物进行监测 技术和其他模式;然而，评估多污染物暴露的综合健康影响仍然是一个挑战。 挑战.为了满足这一需求，我们建议开发生物加权多污染物暴露表面， 联合收割机多种空气污染物和健康影响。例如，心血管健康的相关机制可能包括 血压的变化。通过这种方法，可以开发出反映空气预期影响的单个表面 污染混合物对特定地理区域特定生理效应的影响。我们还旨在整合这些表面 在一个交通模型中，使我们能够捕捉交通相关的空气污染和交通政策对健康的影响， 大城市规模的场景。