Exploring the Development of Biologically-Weighted Multi-Pollutant Exposure Surfaces for the Evaluation of Air Pollution Health Effects

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Population-based studies of the health effects of air pollution increasingly rely on exposure surfaces to assign exposures to large numbers of study participants. Such surfaces are available for a growing list of air pollutants through satellite technology and other models; however, evaluating the integrated health effects of multi-pollutant exposures remains a challenge. To address this need, we propose the development of biologically weighted multi-pollutant exposure surfaces that combine multiple air pollutants and health effects. For example, relevant mechanisms for cardiovascular health may include changes in blood pressure. Through this approach, a single surface is developed that reflects the expected impact of air pollution mixtures on specific physiological effects across a given geographical area. We also aim to integrate these surfaces within a transportation model allowing us to capture the traffic-related air pollution and health effects of transport policy scenarios at a metropolitan scale.