Pharmaceutical Technology: Controlled Drug Delivery Systems

制药技术：受控药物输送系统

• 批准号: 489247-2015
• 负责人: Dorsnie, Ronnie
• 金额: $ 7.29万
• 依托单位: Cégep John Abbott College
• 依托单位国家: 加拿大
• 项目类别: College and Community Innovation Program - Entry Level
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=586457
• 关键词: Pharmaceutical; Technology; Controlled; Drug; Delivery

Three years ago, John Abbott College, located in the Montreal West Island launched a new career program related to Pharmaceutical Production Technology, as well as a new department. Since two years, Dr Khalid has been very active in performing applied research at the College, where 9 of our students were regularly involved. He has also been very active in establishing communication channels with local and regional pharmaceutical companies in order to identify how their applied research needs could fit with our departmental mission, ambitions and expertise. John Abbott College (main participant Dr Khalid) would like to submit this application to the College and Community Innovation Program - Entry-Level Innovation Enhancement Grant. This type of financial support will enable us to build our research capacity in order to perform specific applied research projects in collaboration with local industries such Altus Formulation, Importfab, and Sobio Pharmaceuticals. The technology platform suggested in the three projects will respond to this need by providing access to an impressive range of equipment as well as specialized expertise in drug formulation. The choice of projects for this application was done considering the technology transfer feasibility. The three projects are: 1. Development and Validation of a Novel Sectable Controlled Release Formulation of Acetaminophen 2. Formulation of polymer based microcapsules using spray drying for controlled release of poorly water soluble drugs (BCS class II) and as taste masking device 3. Formulation development of polymeric microcapsules using interfacial cross-linking

三年前，位于蒙特利尔西岛的John Abbott学院推出了一项与制药生产技术相关的新职业计划，以及一个新的部门。自两年以来，哈立德博士一直非常积极地在学院进行应用研究，我们的9名学生定期参与其中。他还非常积极地与当地和区域制药公司建立沟通渠道，以确定他们的应用研究需求如何符合我们的部门使命、抱负和专业知识。 约翰雅培学院（主要参与者博士哈立德）想提交此申请的学院和社区创新计划-入门级创新增强补助金。这种类型的财政支持将使我们能够建立我们的研究能力，以便与当地行业（如Altus Formulation，Importfab和Sobio Pharmaceuticals）合作开展具体的应用研究项目。这三个项目中建议的技术平台将通过提供一系列令人印象深刻的设备以及药物配制方面的专门知识来满足这一需要。选择该应用的项目时考虑了技术转让的可行性。这三个项目是： 1.对乙酰氨基酚新型分段控释制剂的开发与验证 2.使用喷雾干燥制备聚合物基微胶囊，用于控制水溶性差的药物（BCS II类）的释放并作为掩味装置 3.界面交联法制备高分子微胶囊