Environmental epigenetics: a mechanistic approach to describing persistent effects of PAHs in birds

环境表观遗传学：描述多环芳烃对鸟类持久影响的机械方法

• 批准号: RGPIN-2015-03925
• 负责人: Head, Jessica
• 金额: $ 2.4万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=589474
• 关键词: Environmental; epigenetics; mechanistic; approach; describing

There is a growing awareness among scientists that exposure to environmental stress early in life can have lasting impacts on health later in life. Some of these persistent effects may be due to chemical modifications to epigenetic marks, such as DNA methylation, in developing embryos. This concept has been the focus of a tremendous amount of research in the biomedical field in recent years, and will have an equally important (and as of yet unrealized) impact on the ecological sciences.

科学家们越来越意识到，在生命早期暴露在环境压力下可能会对晚年的健康产生持久的影响。其中一些持久的影响可能是由于对发育中的胚胎中的表观遗传标记进行了化学修饰，如DNA甲基化。近年来，这一概念一直是生物医学领域大量研究的焦点，并将对生态科学产生同样重要(但尚未实现)的影响。