Translating large-scale brain imaging technologies into deployable mobile technologies

将大规模脑成像技术转化为可部署的移动技术

• 批准号: RGPIN-2015-04018
• 负责人: Cheung, Teresa
• 金额: $ 1.6万
• 依托单位: Simon Fraser University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=589539
• 关键词: Translating; large; scale; brain; imaging

Brain wave technologies such as electroencephalography (EEG) provide an online record of different brain functions. While this low-cost, portable technique has been tremendously useful in recording brain signals for single time point diagnostics at the scalp-level it is difficult to monitor the whole brain because using EEG alone to compute brain activity can be inaccurate. This makes it difficult to distinguish signals from different areas of the brain. At present, analysis and targeting of specific regions of the brain can be accomplished only using expensive, access-limited neuroimaging devices such as functional MRI (fMRI) and magnetoencephalography (MEG) combined with anatomical MRI scans. Even though, EEG and MEG signals originate from the same neurophysiological processes, there are important differences. Magnetic fields are less distorted than electric fields by the skull and scalp, which results in a better spatial resolution of the MEG, allowing signals to be localized with more accuracy. The high cost and lack of portability of fMRI and MEG limits their use in point-of-care settings where portability or frequent imaging can benefit outcomes.

脑电波技术，如脑电图（EEG）提供了不同的大脑功能的在线记录。虽然这种低成本的便携式技术在记录用于头皮水平的单时间点诊断的脑信号方面非常有用，但是难以监测整个大脑，因为单独使用EEG来计算大脑活动可能是不准确的。这使得很难区分来自大脑不同区域的信号。目前，只能使用昂贵的、访问受限的神经成像设备，如功能性MRI（fMRI）和脑磁图（MEG）结合解剖MRI扫描来完成对大脑特定区域的分析和靶向。尽管EEG和MEG信号起源于相同的神经生理过程，但存在重要的差异。磁场比电场更少地被头骨和头皮扭曲，这导致MEG的更好的空间分辨率，从而允许更准确地定位信号。功能磁共振成像和脑磁图的高成本和缺乏便携性限制了它们在护理点环境中的使用，在护理点环境中，便携性或频繁成像可以有益于结果。