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Role of dopamine in the maturation of prefrontal cortex and associated behaviors.

Role of dopamine in the maturation of prefrontal cortex and associated behaviors.
多巴胺在前额皮质成熟和相关行为中的作用。
批准号:
RGPIN-2015-04761
负责人:
Srivastava, Lalit
金额:
$2.4万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31

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中文摘要
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英文摘要
The refinement of mature cognitive, motivational and social behaviors typically takes place during adolescence, and is linked to the protracted development of the prefrontal cortex (PFC). Among neural inputs to the PFC, the mesofrontal dopamine (DA) system is interesting as DAergic afferents peak when key organizational events are taking place in the PFC. DAergic signaling, besides its acute effects on cortical excitatory and inhibitory neuron excitability, also mediates synaptic remodeling and long-term plasticity. While a large body of literature exists on the role of adult DA system, very little is known of the long-term consequences of early dysregulated DA homeostasis on the development of prefrontal networks and associated behaviors.
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Role of dopamine in adolescent maturation of prefrontal cortical circuits and associated behaviors
  • 批准号:
    RGPIN-2020-05046
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2022
  • 负责人:
    Srivastava, Lalit
  • 依托单位:
Role of dopamine in adolescent maturation of prefrontal cortical circuits and associated behaviors
  • 批准号:
    RGPIN-2020-05046
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2021
  • 负责人:
    Srivastava, Lalit
  • 依托单位:
Role of dopamine in adolescent maturation of prefrontal cortical circuits and associated behaviors
  • 批准号:
    RGPIN-2020-05046
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2020
  • 负责人:
    Srivastava, Lalit
  • 依托单位:
Role of dopamine in the maturation of prefrontal cortex and associated behaviors.
  • 批准号:
    RGPIN-2015-04761
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.4万
  • 财政年份:
    2019
  • 负责人:
    Srivastava, Lalit
  • 依托单位:
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