Evolution of hypervariable flax orbitides
Evolution of hypervariable flax orbitides
批准号:
RGPIN-2015-05516
负责人:
Reaney, Martin
金额:
$2.46万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31
中文摘要
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英文摘要
Natural products are the basis for most medicines and biologically active substances. It was thought that enzymes produced most natural products but it was recently discovered that ribosomes also produce natural product precursors. Plants, mammals, bacteria and fungi all produce N to C cyclized peptide natural products. The accumulation of cyclic peptides can be significant and the number of possible new natural products is staggering. There are more potential peptides than known compounds. Cyclic peptides called orbitides have been discovered in a range of food and medicinal plants.
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