Parallel syntheis reactor

合成有机化学产生了改变植物油性质的途径，其中许多是众所周知的。不幸的是，很少有工艺在经济上足够可行，可供工业使用。因此，有必要将这些过程付诸实践，以生产各种各样的增值消费品和工业产品。本提案中定义的设备旨在筛选将植物油转化为改进的消费品和工业产品的有效工业工艺。用于新合成的植物油将衍生自具有独特化学性质和/或低成本的加拿大作物，包括：卡诺拉、亚麻、高油酸卡诺拉、索林亚麻、芫荽、亚麻荠和油菜籽。该设备提供了参与平行合成方法的能力，这可以大大加快有用反应的开发，以生产新产品。 改性油将在良好控制的条件下通过一系列反应合成。将开发将植物油廉价地转化为以下产品的方法：1）在低温（-40 ℃）下保持液体; 2）具有低粘度（<4 cP）; 3）具有高粘度（>200 cP）; 4）具有高极性; 5）具有低极性; 6）具有增强的氧化稳定性（>10 h AOM）7）更容易聚合。 申请人已经开发了专利方法和商业秘密来制备用于工业应用的烷基酯和共轭脂肪酸。该设备将用于培养硕士和博士。该研究所的研究人员将为候选人以及技术人员和博士后研究员提供培训，以进行油改性化学，并探索各种反应来改变脂质的相关性质。

Synthetic organic chemistry yields routes to change the properties of plant oils and many are well known. Unfortunately, few of the processes are sufficiently economically feasible for use by industry. It is necessary therefore, to reduce these processes to practice in order to produce a wide variety of value-added consumer and industrial products. The equipment defined in this proposal is designed to screen for efficient industrial processes for converting vegetable oils to improved consumer and industrial products. The vegetable oils used in novel syntheses will be derived from Canadian crops having a unique chemistry and/or low cost ,including; canola, flax, high-oleic canola, solin flax, coriander, camelina and rapeseed. The equipment provides the ability to engage in parallel synthetic approaches which can greatly accelerate development of useful reactions to produce new products.   Modified oils will be synthesized through a series of reactions under well controlled conditions. Processes will be developed to inexpensively convert vegetable oils to products that: 1) remain liquid at low temperature (-40C); 2) have low viscosity (<4 cP); 3) have high viscosity (>200 cP); 4) have high polarity; 5) have low polarity; 6) have enhanced oxidative stability (>10 h AOM) 7) are more readily polymerized.   Patented methods and trade secrets have been developed by the applicant to prepare alkyl esters and conjugate fatty acids for industrial applications. The equipment will be used in training M.Sc. and Ph.D. candidates, as well as technicians and Postdoctoral Fellows, to conduct oil modification chemistry and to explore a wide range of reactions to modify the relevant properties of the lipids.