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Structure, dynamics and causality in protein interaction networks

Structure, dynamics and causality in protein interaction networks
蛋白质相互作用网络的结构、动力学和因果关系
批准号:
RGPIN-2015-05707
负责人:
Michnick, Stephen
金额:
$3.79万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31

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中文摘要
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英文摘要
Problem and Hypothesis: The importance of protein-protein interactions (PPIs) to biology is reflected in the enormous efforts to study them on a large scale, including our own efforts, which resulted in a first description of a PPI network in vivo (Tarassov, et al. Science, 2008). In the past funding period we have developed and validated a novel approach to study dynamics of biochemical networks and to determine protein functions, discovery of pathways and a novel mechanism of allostery. The method is based on measuring dynamics of homomeric protein complexes (HPC) on a large scale.
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Dynamic protein interaction networks to map molecular origins of envronmental and genomic variations.
  • 批准号:
    RGPIN-2021-03216
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.23万
  • 财政年份:
    2022
  • 负责人:
    Michnick, Stephen
  • 依托单位:
Dynamic protein interaction networks to map molecular origins of envronmental and genomic variations.
  • 批准号:
    RGPIN-2021-03216
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.23万
  • 财政年份:
    2021
  • 负责人:
    Michnick, Stephen
  • 依托单位:
Structure, dynamics and causality in protein interaction networks
  • 批准号:
    RGPIN-2015-05707
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.79万
  • 财政年份:
    2019
  • 负责人:
    Michnick, Stephen
  • 依托单位:
Structure, dynamics and causality in protein interaction networks
  • 批准号:
    RGPIN-2015-05707
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.79万
  • 财政年份:
    2018
  • 负责人:
    Michnick, Stephen
  • 依托单位:
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