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Role of NOD-like receptors and inflammasome activation in innate immunity to pathogenic bacteria

Role of NOD-like receptors and inflammasome activation in innate immunity to pathogenic bacteria
NOD样受体和炎症小体激活在病原菌先天免疫中的作用
批准号:
RGPIN-2015-06560
负责人:
Ulanova, Marina
金额:
$2.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31

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中文摘要
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英文摘要
Intracellular NOD-like receptors (NLRs) sense pathogen-associated molecular patterns (PAMPs) and "danger signals", and consequently mediate host response leading to pathogen elimination. Activation of NLRs results in the assembly of inflammasomes required for the activation of caspase-1 followed by IL-1ß precursor processing into the biologically active IL-1ß. It was recently discovered that
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Role of NOD-like receptors and inflammasome activation in innate immunity to pathogenic bacteria
  • 批准号:
    RGPIN-2015-06560
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.19万
  • 财政年份:
    2019
  • 负责人:
    Ulanova, Marina
  • 依托单位:
Role of NOD-like receptors and inflammasome activation in innate immunity to pathogenic bacteria
  • 批准号:
    RGPIN-2015-06560
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.19万
  • 财政年份:
    2018
  • 负责人:
    Ulanova, Marina
  • 依托单位:
Role of NOD-like receptors and inflammasome activation in innate immunity to pathogenic bacteria
  • 批准号:
    RGPIN-2015-06560
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.19万
  • 财政年份:
    2017
  • 负责人:
    Ulanova, Marina
  • 依托单位:
Role of NOD-like receptors and inflammasome activation in innate immunity to pathogenic bacteria
  • 批准号:
    RGPIN-2015-06560
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.19万
  • 财政年份:
    2016
  • 负责人:
    Ulanova, Marina
  • 依托单位:
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  • 项目类别:
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  • 项目类别:
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    --
  • 批准年份:
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  • 负责人:
    韦细端
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