权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Programmable High-Frequency Ultrasound Platform for Translational Biomedical Research

用于转化生物医学研究的可编程高频超声平台

基本信息

批准号：
RTI-2016-00323
负责人：
Zemp, Roger
金额：
$ 10.93万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Research Tools and Instruments
财政年份：
2015
资助国家：
加拿大
起止时间：
2015-01-01 至 2016-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=591408
关键词：
Programmable Frequency Ultrasound Platform Translational

项目摘要

A novel programmable ultrasound array system is requested with high-frequency capabilities, high-intensity therapeutic output capabilities, ultrafast acquisition speeds (>5000 frames/sec), arbitrary waveform capabilities, and full programmability. The system will be a key piece of instrumentation for our multidisciplinary work in biomedical photoacoustic & ultrasound imaging. It will be used to interface to novel 2D micromachined array transducers, to enable high-frequency photoacoustic- and ultrasound molecular imaging, to permit novel ultrasound-aided biomarker release and ultrasound drug-delivery experiments, to enable novel near-orthogonal coded parallel fast imaging schemes, to enable novel ultrasound scattering-tensor imaging and tractography, and to migrate novel photoacosutic functional imaging methods to the clinic. These projects involve a wide array of clinical and basic science collaborators at the University of Alberta and other institutions. The system will support the work and collaborative projects of over 24 trainees presently, with potentially many more users in the future. The system requested has novel per-channel arbitrary-waveform capabilities, deep memory, fast-streaming capabilities, high-frequency capabilities, high-output capabilities, and full programmability, unlike most other ultrasound platforms and would be the first of it's kind in Canada to our knowledge. While other ultrasound platforms exist on campus, none of them are equipped with the proposed capabilities, hampering a large number of promising projects.

要求一种新型的可编程超声阵列系统具有高频能力、高强度治疗输出能力、超快采集速度（>5000帧/秒）、任意波形能力和完全可编程性。该系统将成为我们在生物医学光声和超声成像多学科工作中的关键仪器。它将用于连接到新型2D微机械阵列换能器，实现高频光声和超声分子成像，允许新型超声辅助生物标志物释放和超声药物递送实验，实现新型近正交编码并行快速成像方案，实现新型超声散射张量成像和纤维束成像，并将新型光声功能成像方法迁移到临床。这些项目涉及阿尔伯塔大学和其他机构的广泛的临床和基础科学合作者。该系统目前将支持超过24名受训人员的工作和协作项目，将来可能会有更多的用户。所要求的系统具有新颖的每通道任意波形功能，深度存储器，快速流功能，高频功能，高输出功能和完全可编程性，与大多数其他超声平台不同，据我们所知，这将是加拿大的第一个同类产品。虽然校园里有其他超声平台，但没有一个具备拟议的功能，阻碍了大量有前途的项目。