HIGH FREQUENCY ULTRASOUND FOR EXPERIMENTAL PHYSIOLOGY IN SMALL VERTEBRATES

我们拥有研究发育、生殖、应激和心肺机制专业知识的多学科研究人员团队要求提供资金，以采购最先进的高频超声成像设备，以支持各种研究和培训计划。在大学或附近没有研究小组可以接触到的具有类似能力的其他单位或设备。高频超声设备将提供斑马鱼、小青蛙或小老鼠等活动物软组织和器官功能的前所未有的细节，从而显著提高研究产出。该设备将使我们能够研究斑马鱼的心脏如何应对压力和环境挑战，了解新的激素如何调节性器官，开发繁殖稀有和濒危两栖动物的策略，以及了解内分泌干扰化学物质如何作用于性腺。我们的HQP将为应用于动物发育、生理学和生殖生物学等领域的复杂成像方法和大数据集分析所需的尖端培训提供宝贵的机会。我们为我们的总部提供了一个协作和包容的环境。他们将受到学术界、产业界或政府研究部门的高度追捧，因为他们在我们的研究项目中获得了独特的动手培训和可转让的技能。

Our multidisciplinary team of researchers with expertise in studying developmental, reproductive, stress and cardiorespiratory mechanisms requests funding to procure a state-of-the-art high frequency ultrasound imaging device to support diverse research and training programs. There is no other unit or equipment with similar capabilities available at the University or in the vicinity that is accessible by the research team. The high frequency ultrasound equipment will significantly increase research output by providing unprecedented details of soft tissue and organ function in living animals as small as a zebrafish, a tiny frog or a mouse. The equipment will allow us to study how the zebrafish heart responds to stress and environmental challenges, to understand how novel hormones regulate sex organs, to develop strategies to breed rare and endangered amphibians, and to understand how endocrine-disrupting chemicals act on the gonads. Our HQP will be provided with an invaluable opportunity for the cutting-edge training needed for complex imaging methods and large dataset analysis as applied to fields such as animal development and physiology and reproductive biology. We provide a collaborative and inclusive environment for our HQP. They will be highly sought after by academia, industry, or government research departments because of the unique hands-on training and transferable skills that they gain in our research program.