Neuraminidase 1 as a trigger of immune thrombocytopenia: using animal models to understand pathophysiology of the disease and develop novel therapies.

神经氨酸酶 1 作为免疫性血小板减少症的触发因素：利用动物模型了解该疾病的病理生理学并开发新疗法。

• 批准号: 346871
• 负责人: Pshezhetsky Alexey V
• 金额: $ 51.8万
• 依托单位: Centre hospitalier universitaire Sainte-Justine (Montral, Qubec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2021-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=346871&lang=en
• 关键词: Lysosome; Macrophage; Neuraminidase; Platelet; Sialidase; Thrombocytopenia

This project concerns thrombocytopenia, a disease of blood coagulation caused by low counts of blood cells called platelets or thrombocytes. Some individuals with thrombocytopenia may experience external bleeding such as nosebleeds, and/or bleeding gums.

这个项目涉及血小板减少症，一种由称为血小板或血小板的血细胞计数低引起的血液凝固疾病。一些血小板减少症患者可能会出现外部出血，如鼻出血和/或牙龈出血。