Improving the accuracy of cardiac PET with motion-free imaging.

心脏正电子发射断层扫描（PET）使用微量的放射性标记化合物（称为示踪剂）对心脏进行成像。动态PET使用专门的扫描仪在几分钟内对患者进行成像，在注射示踪剂分布在患者体内时拍摄一系列快照。动态图像然后可以由专门的软件处理，以测量示踪剂与体内组织相互作用的速率。这些速率可用于评估生理功能。在心脏PET中，我们使用这些方法来测量功能，如心肌（心肌）血流量（MBF），可用于检测心脏供血减少。PET MBF测量是基础研究中用于了解疾病和测量治疗有效性的领先工具，并且正在成为重要的临床工具。

Cardiac positron emission tomography (PET) uses a minute amount of radioactive labelled compound, called a tracer, to image the heart. Dynamic PET uses a specialized scanner to image the patient over several minutes, taking a series of snap shots of the injected tracer as it distributes through the patient's body. The dynamic images can then be processed by specialized software to measure the rates at which the tracer interacts with the tissues in the body. These rates can be used to assess physiologic function. In cardiac PET we use these methods to measure functions such as myocardial (heart muscle) blood flow (MBF), which can be used to detect reduced blood supply to the heart. PET MBF measurement is a leading tool in basic research for understanding disease and measuring therapy effectiveness, and is emerging as an important clinical tool.