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Unraveling the Mechanism of Action of the Adiponectin Receptor Pathways in a Humanized in vitro Model of Carotid Plaque Instability

Unraveling the Mechanism of Action of the Adiponectin Receptor Pathways in a Humanized in vitro Model of Carotid Plaque Instability
揭示颈动脉斑块不稳定人源化体外模型中脂联素受体途径的作用机制
批准号：
347276
负责人：
Daskalopoulou Stella S
金额：
$83.82万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=347276&lang=en
关键词：
Adiponectin Adiponectin Receptors Atherosclerosis Carotid Plaque Histology Carotid Plaque Instability Gene And Protein Expression Immunomodulation Macrophage Polarization Monocytes Stroke

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Every 10 minutes a Canadian has a stroke, which kills ~14,000 Canadians yearly. Strokes are mainly caused by fatty deposit build-ups (plaques) in the arteries of the neck, which can break-off and travel to the brain. It is important to find out early when
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