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CDK4 regulation of breast cancer stem cells - A novel prognostic marker and therapeutic target for triple-negative breast cancer and chemotherapy-resistant tumors.

CDK4 regulation of breast cancer stem cells - A novel prognostic marker and therapeutic target for triple-negative breast cancer and chemotherapy-resistant tumors.
CDK4对乳腺癌干细胞的调节——三阴性乳腺癌和化疗耐药肿瘤的新型预后标志物和治疗靶点。
批准号:
345984
负责人:
Lebrun Jean-Jacques
金额:
$71.57万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2021-03-01

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中文摘要
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英文摘要
Metastatic cancer is a largely incurable disease and responsible for 90% of human cancer-related deaths. Cancer stem cells (CSCs) are capable of driving not only tumor initiation, but also metastasis in various human cancer types. This distinct subpopulat
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Exploiting a novel dual-specificity cell cycle inhibitor, KP108 as a therapeutic approach for metastatic breast cancer
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    469188
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  • 资助金额:
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  • 财政年份:
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海外基金
抗LAG3抗体改善免疫微环境逆转CDK4/6抑制剂 耐药的机制研究
  • 批准号:
    JCZRLH202600287
  • 项目类别:
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  • 资助金额:
    --
  • 批准年份:
    2026
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