Monoclonal antibodies against dominant Francisella antigens.

针对主要弗朗西斯菌抗原的单克隆抗体。

• 批准号: 499047-2016
• 负责人: Nano, Francis
• 金额: $ 1.79万
• 依托单位: University of Victoria
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=607160
• 关键词: Monoclonal; antibodies; against; dominant; Francisella

In the proposed work we will develop monoclonal antibodies against dominant antigens of Francisella species. The antibodies can be used in immunofluorescence and Western immunoblots in research activities, and in ELISA and other methodologies for clinical diagnostics. The antibodies that will be developed will have broad reactivity with several Francisella species and will have value in studying both human and animal pathogenic species.

在拟议的工作中，我们将开发针对弗朗西斯氏菌优势抗原的单抗。该抗体可用于研究活动中的免疫荧光和免疫印迹，以及用于临床诊断的ELISA法和其他方法。将开发的抗体将与几个弗朗西塞氏菌物种具有广泛的反应性，并将在研究人类和动物致病物种方面具有价值。