Approaches to whole bacterial genome cloning and species switching

全细菌基因组克隆和物种转换的方法

• 批准号: RGPIN-2017-03727
• 负责人: Nano, Francis
• 金额: $ 1.89万
• 依托单位: University of Victoria
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=629727
• 关键词: Approaches; whole; bacterial; genome; cloning

The microbial world consists of more than a million species of bacteria that live in a wide variety of environmental niches, including boiling water, extremes of pH, radioactive rocks, and sub-zero sea ice. In order to study a bacterium or exploit its biodiversity for human benefits, microbiologists need to cultivate a bacterium in the laboratory as a pure culture. However, a large proportion of the world’s bacteria are difficult or impossible to cultivate in pure culture.

微生物世界由一百多万种细菌组成，它们生活在各种各样的环境中，包括沸水、极端pH值、放射性岩石和零度以下的海冰。为了研究细菌或利用其生物多样性造福人类，微生物学家需要在实验室中将细菌培养为纯培养物。然而，世界上很大一部分细菌很难或不可能在纯培养中培养。