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Cellular and molecular characterization of T cell development for immune-reconstitution

Cellular and molecular characterization of T cell development for immune-reconstitution
免疫重建 T 细胞发育的细胞和分子特征
批准号：
354632
负责人：
Zuniga-Pflucker Juan C
金额：
$203.18万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2023-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=354632&lang=en
关键词：
Gamma-Delta T Cells Hematopoietic Stem Cells Immune Reconstitution Notch Signaling T Cell Development Thymus

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中文摘要
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英文摘要
The proposed research focuses on blood cell development, and, in particular, on how a subset of white blood cells, known as T lymphocytes, are generated. T cells are important effectors and master regulators of the immune system, which protects us from ca
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Notch signaling in the generation of mature naïve conventional and regulatory T cells
Study of pre- and gamma/delta-T cell receptor signals regulating thymocyte differentiation
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号：
    256472
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2011
  • 负责人：
    Zuniga-Pflucker Juan C
  • 依托单位：
    University of Toronto
Characterization and lineage commitment of progenitor thymocytes
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