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Study of pre- and gamma/delta-T cell receptor signals regulating thymocyte differentiation

Study of pre- and gamma/delta-T cell receptor signals regulating thymocyte differentiation
前T细胞和γ/δT细胞受体信号调节胸腺细胞分化的研究
批准号：
280388
负责人：
Zuniga-Pflucker Juan C
金额：
$56.08万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-03-01 至 2018-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=280388&lang=en
关键词：
Delta-Like Eva1 Immune Reconstitution Lymphocyte Development Lymphocyte Progenitors Notch Signaling Stromal Cells T Cell Development Thymus Thymus Epithelial Cells

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中文摘要
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英文摘要
The thymus is the essential organ that supports and allows for the development of T lymphocytes from bone marrow-derived stem cells. Thymic contributions result in the generation of mature T cells that are capable of recognizing foreign antigens/pathogens
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Notch signaling in the generation of mature naïve conventional and regulatory T cells
Cellular and molecular characterization of T cell development for immune-reconstitution
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号：
    256472
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2011
  • 负责人：
    Zuniga-Pflucker Juan C
  • 依托单位：
    University of Toronto
Characterization and lineage commitment of progenitor thymocytes
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