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Characterization and lineage commitment of progenitor thymocytes

Characterization and lineage commitment of progenitor thymocytes
胸腺细胞祖细胞的特征和谱系定型
批准号：
219984
负责人：
Zuniga-Pflucker Juan C
金额：
$7.29万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-09-01 至 2011-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=219984&lang=en
关键词：
Delta-Like Eva1 Immune Reconstitution Lymphocyte Development Lymphocyte Progenitors Notch Signaling Stromal Cells T Cell Development Thymus Thymus Epithelial Cells

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中文摘要
翻译
胸腺是产生T细胞的主要器官，T细胞在我们抵御传染病和癌症方面起着关键作用。然而，T细胞发育的改变可导致致病T细胞的产生，从而导致ma
英文摘要
The thymus is the principal organ for the generation of T cells, which play a key role in our defense against infectious diseases and cancer. However, alterations in T cell development can lead to the generation of pathogenic T cells that contribute to ma
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会议论文
Notch signaling in the generation of mature naïve conventional and regulatory T cells
Cellular and molecular characterization of T cell development for immune-reconstitution
Study of pre- and gamma/delta-T cell receptor signals regulating thymocyte differentiation
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号：
    256472
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2011
  • 负责人：
    Zuniga-Pflucker Juan C
  • 依托单位：
    University of Toronto
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