Mechanisms of ERK-dependent tumor suppression
Mechanisms of ERK-dependent tumor suppression
批准号:
355588
负责人:
Ferbeyre Gerardo
金额:
$50.99万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2021-10-01
中文摘要
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英文摘要
Cellular senescence is a stable cell cycle arrest triggered by stresses that can cause cancer. Some cancer causing genes can activate this program in normal cells. The prototype senescence inducer is oncogenic RAS, a gene that is mutated in 30% of human c
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