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Regulation of senescence and aging by the axis STAT5-SOCS1-p53

Regulation of senescence and aging by the axis STAT5-SOCS1-p53
STAT5-SOCS1-p53 轴对衰老和老化的调节
批准号:
209647
负责人:
Ferbeyre Gerardo
金额:
$50.59万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-09-01 至 2015-09-01

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英文摘要
Aging is strongly linked to chronic inflammation but the molecular basis of this relationship is poorly understood. Inflammation involves a family of molecules known as cytokines. At the cellular levels cytokine signaling can accelerate the aging process
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Targeting ribosomal RNA biogenesis to restore the senescence tumor suppression mechanism
Elimination of senescent cells to treat estrogen-deprivation associated disorders
Molecular mechanisms of oncogene-induced senescence
Targeting senescence cells in pancreatic cancer
  • 批准号:
    364242
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2017
  • 负责人:
    Ferbeyre Gerardo
  • 依托单位:
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