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Cellular and molecular mechanisms regulating the progression of atherosclerosis: exploiting macrophage reverse transendothelial migration as a therapeutic strategy

Cellular and molecular mechanisms regulating the progression of atherosclerosis: exploiting macrophage reverse transendothelial migration as a therapeutic strategy
调节动脉粥样硬化进展的细胞和分子机制:利用巨噬细胞逆向跨内皮迁移作为治疗策略
批准号:
355119
负责人:
Cybulsky Myron I
金额:
$236.52万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2023-10-01

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中文摘要
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英文摘要
Atherosclerosis is a chronic inflammatory disease of arteries and remains the principal cause of death in our society despite effective cholesterol-lowering therapies. Atherosclerosis develops silently for decades before causing heart attacks and strokes.
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Canada Research Chair - Tier 1
  • 批准号:
    459668
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2021
  • 负责人:
    Cybulsky Myron I
  • 依托单位:
Inflammatory functions of lipid-laden macrophages in early atherosclerosis.
  • 批准号:
    322598
  • 项目类别:
    Operating Grants
  • 资助金额:
    $52.34万
  • 财政年份:
    2015
  • 负责人:
    Cybulsky Myron I
  • 依托单位:
Canada Research Chair Tier 1
  • 批准号:
    332845
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2014
  • 负责人:
    Cybulsky Myron I
  • 依托单位:
Stabilization of integrin-mediated monocyte adhesion to inflamed vascular endothelium: actin dynamics and signaling.
  • 批准号:
    280212
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.01万
  • 财政年份:
    2013
  • 负责人:
    Cybulsky Myron I
  • 依托单位:
海外基金