Small molecules targeting aberrant STAT3 activity: killing breast tumour cells and inducing an anti-tumour immune response.
Small molecules targeting aberrant STAT3 activity: killing breast tumour cells and inducing an anti-tumour immune response.
批准号:
355181
负责人:
Gunning Patrick T
金额:
$56.84万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2020-10-01
中文摘要
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英文摘要
Here, we describe a class of novel drug-like molecules that potently and selectively kill both Her2+ and triple negative breast cancer cells over normal healthy cells. These molecules target a protein called STAT3, that has been shown to play a key role i
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