Exploiting mesenchymal stem cell mechanobiology to enhance the success of burn wound cell therapy.

利用间充质干细胞力学生物学来提高烧伤创面细胞治疗的成功率。

• 批准号: 362321
• 负责人: Walraven Mariëlle
• 金额: $ 9.83万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-11-01 至 2019-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=362321&lang=en
• 关键词: Bone-Marrow Derived Stem Cells; Cell Culture Techniques; Cell Therapy; Epigenetic Modifiers; Large Area Skin Burn Wounds; Proteomics; Scarring And Fibrosis; Soft-Priming Culture Method; Tissue Regeneration; Wound Healing

Health Significance: Dysregulated healing of large area skin wounds is a leading cause of morbidity following burns. Because our body is overwhelmed with the injury and the pool of available cells is rapidly exhausted, large burn wounds accumulate disfigu

健康意义：大面积皮肤伤口愈合失调是烧伤后发病率的主要原因。由于我们的身体因创伤而不堪重负，可用细胞池迅速耗尽，大面积烧伤创面会积累畸形。