Fluorinated amino acids as PET radiotracers for Central Nervous System (CNS) imaging and therapeutic applications

氟化氨基酸作为 PET 放射性示踪剂，用于中枢神经系统 (CNS) 成像和治疗应用

• 批准号: 520621-2017
• 负责人: Britton, Robert
• 金额: $ 1.09万
• 依托单位: Simon Fraser University
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=618938
• 关键词: Fluorinated; amino; acids; PET; radiotracers

SFU's Innovation Office helps SFU innovators assess the patentability and market potential of new technologies and research innovations. The goal is to transfer this knowledge for the benefit of our communities, society and the economy. The Innovation Office's services include confidential invention disclosures, technology assessments, patentability reviews, market assessments, intellectual property protection and commercialization assistance.The Britton Group and SFU focuses on research for the development of concise and stereoselective synthetic methods and strategies that permit rapid access to biologically important natural products and drugs. Recently, the Britton group has developed several convenient strategies to incorporate a fluorine atom into a molecule that has potentially useful biological activity. This discovery has formed the basis of several productive collaborations and has created new opportunities for drug discovery and molecular diagnostics using 18F positron emission tomography (PET) imaging. SFU's Innovation Office has contacted Adventus Research + Consulting to request a market study of a technology titled "Fluorinated Amino Acids as PET Radiotracers for Central Nervous System (CNS) Imaging and Therapeutic Applications".

SFU的创新办公室帮助SFU创新者评估新技术和研究创新的可专利性和市场潜力。我们的目标是为了我们的社区，社会和经济的利益转移这些知识。创新办公室的服务包括发明机密披露、技术评估、专利性审查、市场评估、知识产权保护和商业化协助。布里顿集团和SFU专注于研究开发简洁和立体选择性的合成方法和策略，以快速获得具有生物重要性的天然产物和药物。最近，布里顿小组已经开发了几种方便的策略，将氟原子引入具有潜在有用生物活性的分子中。这一发现已经形成了几个富有成效的合作的基础，并创造了新的机会，药物发现和分子诊断使用18F正电子发射断层扫描（PET）成像。SFU的创新办公室已经联系了Adventus Research + Consulting，要求对一项名为“氟化氨基酸作为PET放射性示踪剂用于中枢神经系统（CNS）成像和治疗应用”的技术进行市场研究。