An assessment of market opportunities for "nano-biomineralizable varnish for tooth remineralization"

“用于牙齿再矿化的纳米生物矿化清漆”的市场机会评估

• 批准号: 508648-2017
• 负责人: Kishen, Anil
• 金额: $ 1.08万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=619179
• 关键词: assessment; market; opportunities; nano; biomineralizable

Our laboratory has developed and characterized a non-fluoridated dental varnish that protects teeth against dental caries, increases remineralization of the dental surface and also decreases hypersensitivity. The novelty of the varnish is that it contains a chitosan nanoparticle that prevents biofilm formation and promotes remineralization of the tooth. The nano-varnish also does not contain fluoride; the "go-to" agent for dental caries prevention on the market. There has been growing public concern about fluoride-based dental products for the prevention of dental caries and the remineralization of teeth in young children. Studies have shown that children consuming too much fluoride (swallowing fluoride containing dental products such as varnishes and toothpaste) can acquire "fluorosis" of the teeth. This condition causes white or brown discoloration or spots on teeth. Over 30 studies have associated elevated fluoride exposure with neurological impairment in children. In addition, most fluoride-based varnishes on the market do not provide significant remineralization of the tooth or antibacterial properties that decrease biofilm formation on the tooth. Our nano-varnish can be produced at a low-cost and can be used in infants, young children and adults. Dr. Kishen and his team have extensive expertise in the production of nanoparticles for multiple dental therapeutic markets. The main aim of the purpose of the market assessment is to determine market parameters and to validate the value proposition of the novel of the varnish with end-users. Adventus will be hired to determine market trends, market size, the competitive landscape and barriers to entry for the varnish. This analysis should provide the basis for the commercialization of the varnish and will assist the team in determining what factors will enhance product adoption by end-users.

我们的实验室已经开发并表征了一种非氟化的牙齿保护漆，可以保护牙齿免受龋齿，增加牙齿表面的矿化，并降低过敏。这种保护漆的新奇在于它含有一种壳聚糖纳米颗粒，可以防止生物膜的形成，促进牙齿的矿化。纳米清漆也不含氟化物;市场上预防龋齿的“首选”代理。公众越来越关注含氟牙科产品对预防龋齿和幼儿牙齿矿化的影响。研究表明，儿童摄入过多的氟化物（吞咽含有氟化物的牙科产品，如清漆和牙膏）可能会患上牙齿的“氟中毒”。这种情况会导致牙齿出现白色或棕色变色或斑点。超过30项研究表明，氟暴露量增加与儿童神经损伤有关。此外，市场上的大多数基于氟化物的清漆不提供显著的牙齿矿化或减少牙齿上生物膜形成的抗菌性能。我们的纳米清漆可以以低成本生产，可用于婴儿，幼儿和成人。Kishen博士和他的团队在为多种牙科治疗市场生产纳米颗粒方面拥有丰富的专业知识。市场评估的主要目的是确定市场参数，并与最终用户一起验证清漆的新颖性的价值主张。Adventus将被聘请来确定市场趋势，市场规模，竞争格局和进入清漆的障碍。该分析将为清漆的商业化提供基础，并将帮助团队确定哪些因素将提高最终用户的产品采用率。