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Regulation of proteostasis by glycosylation of nucleocytoplasmic proteins.

Regulation of proteostasis by glycosylation of nucleocytoplasmic proteins.
通过核细胞质蛋白的糖基化调节蛋白质稳态。
批准号：
372076
负责人：
Vocadlo David
金额：
$57.96万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=372076&lang=en
关键词：
Chemical Biology Heat Shock Mass Spectrometry Nutrient Responsive O-Glcnac O-Glycosylation Protein Glycosylation Protein Stability Proteomics Ubiquitin

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The cells of all organisms need to adapt to changes in their environment. One mechanism enabling adaptation to environmental changes, including variation in nutrient availability and cellular stressors such as heat, is the ability of cells to tune their l
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