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Regulation of cellular proteostasis by glycosylation of nucleocytoplasmic proteins.

Regulation of cellular proteostasis by glycosylation of nucleocytoplasmic proteins.
通过核细胞质蛋白的糖基化调节细胞蛋白质稳态。
批准号：
351779
负责人：
Vocadlo David
金额：
$7.29万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-04-01 至 2017-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=351779&lang=en
关键词：
Chemical Biology Mass Spectrometry Nutrient Responsive O-Glcnac O-Glycosylation Protein Glycosylation Protein Stability Proteomics Ubiquitin

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中文摘要
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英文摘要
The ubiquitous modification of cellular proteins with a specialized sugar known as O-GlcNAc is found in all multicellular organisms. O-GlcNAc is attached to over a thousand proteins and has been shown to be involved in cellular processes ranging from cont
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Regulation of proteostasis by glycosylation of nucleocytoplasmic proteins.
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