Impact of the male germ line on the mutational load carried by mammalian embryos

雄性种系对哺乳动物胚胎携带的突变负荷的影响

• 批准号: DP110103951
• 负责人: Prof Robert Aitken
• 金额: $ 23.9万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-05-17 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110103951
• 关键词: Impact; male; germ; line; mutational

This project examines whether a man's age or exposure to lifestyle factors (alcohol, cigarette smoke and mobile phone radiation) can have a major effect on the health of his children. The project is particularly relevant to the safety of assisted conception procedures used to treat the 1 in 20 Australian men suffering from infertility.

该项目研究男性的年龄或生活方式因素（酒精、吸烟和移动的手机辐射）是否会对其子女的健康产生重大影响。该项目与用于治疗每20名澳大利亚男子中就有1名患有不育症的辅助受孕程序的安全性特别相关。