Molecular genetic of Plant hormone signaling

植物激素信号传导的分子遗传学

• 批准号: RGPIN-2015-06330
• 负责人: McCourt, Peter
• 金额: $ 3.28万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=628900
• 关键词: Molecular; genetic; Plant; hormone; signaling

: Plant hormones are a collection of small structurally unrelated molecules that have profound effects on plant growth and development. Over the past decade, exciting advances have been made to define core-signaling pathways for many hormones. Now plant hormone biology is entering a challenging period of understanding how the information conveyed by these small molecules is turned into cellular responses. Furthermore, we are also entering a stage where information from experimental models needs to be translated to important crops. My research program investigates the fundamental mechanisms of two plant hormones, abscisic acid (ABA) and strigolactones (SLs) with respect to germination and early seedling growth. Here, I propose to use the cutting edge tools of systems and chemical biology to link these hormones to plant growth and development networks in novel ways both at a fundamental level and for biotechnological application.

植物激素是一组结构无关的小分子，对植物的生长和发育有着深远的影响。在过去的十年中，在确定许多激素的核心信号通路方面取得了令人兴奋的进展。现在植物激素生物学正在进入一个具有挑战性的时期，即了解这些小分子传递的信息如何转化为细胞反应。此外，我们也正在进入一个阶段，需要将实验模型的信息转化为重要作物。我的研究计划调查两种植物激素，脱落酸（阿坝）和独脚金内酯（SL）的发芽和早期幼苗生长的基本机制。在这里，我建议使用系统和化学生物学的尖端工具，以新颖的方式将这些激素与植物生长和发育网络联系起来，无论是在基础层面还是在生物技术应用方面。