Commensal fungal metabolism in lymphoid organ development and maintenance

淋巴器官发育和维护中的共生真菌代谢

• 批准号: 368956
• 负责人: Shi Yan
• 金额: $ 61.86万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=368956&lang=en
• 关键词: Commensal Fungi; Dendritic Cells; Gut; Microbiota; Secondary Lymphoid Organs

In our intestine, there is a large cohort of microbes, including bacteria and fungi. Their presence is important for our immune system development. In germ-free mice (no microbes in the gut), lymph nodes in the host are small and incapable of mounting eff

在我们的肠道中，有大量微生物，包括细菌和真菌。它们的存在对于我们免疫系统的发育很重要。在无菌小鼠（肠道中没有微生物）中，宿主的淋巴结很小并且无法发挥作用