Posterior Parietal Cortex Persistent Activity and Working Memory

后顶叶皮层持续活动和工作记忆

• 批准号: RGPIN-2015-06686
• 负责人: Paré, Martin
• 金额: $ 2.11万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=630689
• 关键词: Posterior; Parietal; Cortex; Persistent; Activity

The number of things that humans can hold simultaneously in memory for a short time (our working memory) is remarkably small. The maximum is thought to be seven, as in the number of digits in a phone number, but the average is about only four! The limited capacity of our working memory depends on neural mechanisms that are distributed in the frontal and parietal lobes of our brain, but the current state of our knowledge is far from complete. On the one hand, only basic memory mechanisms have been studied because there exists no adequate animal model to study working memory capacity. On the other hand, nearly all our knowledge about these basic memory mechanisms has been obtained from studies of the frontal cortex despite all the evidence indicating that the parietal cortex also plays an important role.

人类能在短时间内（我们的工作记忆）同时记忆的事物数量非常少。最大值被认为是7位，就像电话号码的位数一样，但平均只有4位！我们有限的工作记忆能力取决于分布在我们大脑额叶和顶叶的神经机制，但我们目前的认识还远远不够。一方面，由于没有足够的动物模型来研究工作记忆容量，因此只研究了基本的记忆机制。另一方面，尽管所有证据表明顶叶皮层也起着重要作用，但我们对这些基本记忆机制的几乎所有知识都是从额叶皮层的研究中获得的。