Cytochrome P450 Family 1 and 3 Function in Aquatic Species
Cytochrome P450 Family 1 and 3 Function in Aquatic Species
批准号:
RGPIN-2016-05767
负责人:
Wilson, Joanna
金额:
$2.55万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
细胞色素P450酶对激素等重要分子的产生和代谢起着至关重要的作用。环磷酰胺对环境污染物的新陈代谢也是至关重要的。细胞色素P450 1和细胞色素P3家族的基因调节异源代谢和类固醇代谢。尽管它们发挥了作用,但我们才刚刚开始了解CYP基因在水生物种中的调节和功能。本实验室在鱼类和水生环节动物中的细胞色素P450的鉴定和研究中发挥了重要作用。两组中新发现的细胞色素P450 1和细胞色素P3家族基因序列提示了新的代谢功能。为了在我们实验室之前完成的研究的基础上,
英文摘要
Cytochrome P450 enzymes (CYPs) are critical for the production and metabolism of important molecules such as hormones. CYPs are also critical for the metabolism of environmental contaminants. Genes in the CYP1 and CYP3 families mediate both xenobiotic and steroid metabolism. Despite their roles, we are only beginning to understand the regulation and function of CYP genes in aquatic species. Our lab has played an important role in the identification and study of CYPs in fish and aquatic annelids. Newly identified CYP1 and CYP3 family gene sequences in both groups suggest novel metabolic functions. To build on research previously completed in our laboratory,
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财政年份:2021
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依托单位:
Cytochrome P450 Family 1 and 3 Function in Aquatic Species
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The impacts of once through cooling on fall and spring spawning fish
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Cytochrome P450 Family 1 and 3 Function in Aquatic Species
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批准号:RGPIN-2016-05767
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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负责人:Wilson, Joanna
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Cytochrome P450 Family 1 and 3 Function in Aquatic Species
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批准号:RGPIN-2016-05767
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资助金额:$2.55万
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依托单位:
Cytochrome P450 Family 1 and 3 Function in Aquatic Species
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批准号:RGPIN-2016-05767
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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负责人:Wilson, Joanna
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The impacts of once through cooling on fall and spring spawning fish
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Cytochrome P450 Family 1 and 3 Function in Aquatic Species
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Behavioural Platforms for Small Aquatic Species
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Effects of thermal, chemical, and radiological emissions on Whitefish
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Function of cytochrome P450 enzymes in aquatic species
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依托单位:
Effects of thermal, chemical, and radiological emissions on Whitefish
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资助金额:$9.25万
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财政年份:2015
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依托单位:
Function of cytochrome P450 enzymes in aquatic species
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Function of cytochrome P450 enzymes in aquatic species
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财政年份:2013
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依托单位:
Function of cytochrome P450 enzymes in aquatic species
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批准号:328204-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.91万
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财政年份:2013
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负责人:Wilson, Joanna
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依托单位:
Function of cytochrome P450 enzymes in aquatic species
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批准号:328204-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.91万
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负责人:Wilson, Joanna
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依托单位:
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批准号:433617-2012
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财政年份:2012
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负责人:Wilson, Joanna
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依托单位:
国内基金
海外基金
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