Medical physics and biomedical research for increased precision in dose measurements and dose computations.

医学物理和生物医学研究，提高剂量测量和剂量计算的精度。

• 批准号: 435510-2013
• 负责人: Beaulieu, Luc
• 金额: $ 3.79万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=633295
• 关键词: Medical; physics; biomedical; research; increased

The ongoing objective of this research program is to increase the accuracy of dose measurements and dose calculations for any radiation based procedures including, but not limited to, radiation therapy, diagnostic and interventional radiology. This is achieved through a comprehensive research program combining elements of basic and applied research in medical physics and biomedical engineering. The program hinges on radiation physics, optics, numerical optimization problems, image and signal processing and high-performance computing.Over the next five year, my research program will be based on four main research tracks, namely 1) development of new radiation dosimeters, 2) applied medical image processing, 3)numerical computation in optimization problems and high precision particle transport and dose calculations and 4) robotic medical devices. We will pursue aggressively our optics-based radiation detector research track for which 1 patent has been granted, 4 new provisional patents taken and 1 technology licensed and commercialized in the last 5 years. We have recently shown proof-of-principal for multi-point scintillation fiber dosimeters, a completely new concept in the field. My laboratory is a recognized world leader in optics-based dosimeter developments and the proposed program is intended to maintain and extend this lead.The proposed research is a highly innovative medical physics and biomedical engineering program. These themes have proven to be extremely productive in term of scientific outputs, patents and HQP training. The proposed program extends the research topics significantly. While the long-term application and commercialization potential are in the medical field (cancer, radiation therapy and radiology), the science discovery and technology development are embedded in a strong science and engineering research program. Our HQP trainees are in high demands. Our program has far reaching impacts: scientific, commercial and ultimately on the quality of life of Canadian through the applications of the said technologies.

该研究计划的持续目标是提高基于辐射程序的剂量测量和剂量计算的准确性，包括但不限于放射治疗，诊断和介入放射学。这是通过一项全面的研究计划来实现的，该计划结合了医学物理和生物医学工程领域的基础研究和应用研究的要素。该程序取决于辐射物理，光学，数值优化问题，图像和信号处理以及高性能计算。在接下来的五年中，我的研究计划将基于四个主要的研究轨道，即1）开发新的放射测量器，2）应用医学图像处理，3）数字计算，3）在医疗问题和高精度粒子和剂量的计算中的数值计算。我们将积极地追求基于光学的辐射探测器研究轨道，该轨道已授予1项专利，4项新的临时专利，并在过去5年中获得了1项技术许可和商业化。我们最近显示了多点闪烁光纤剂量计的原理证明，这是该领域的全新概念。我的实验室是基于光学的剂量仪开发的公认世界领导者，拟议的计划旨在维护和扩展这一线索。拟议的研究是一项高度创新的医学物理和生物医学工程计划。这些主题已被证明在科学产出，专利和HQP培训方面具有极高的生产力。拟议的计划大大扩展了研究主题。尽管长期应用和商业化潜力在医学领域（癌症，放射疗法和放射学），但科学发现和技术发展却嵌入了强大的科学和工程研究计划中。我们的HQP受训者需求很高。我们的计划通过上述技术的应用具有很大的影响力：科学，商业，最终对加拿大人的生活质量。