Medical physics and biomedical research for increased precision in dose measurements and dose computations.

医学物理和生物医学研究，提高剂量测量和剂量计算的精度。

• 批准号: 435510-2013
• 负责人: Beaulieu, Luc
• 金额: $ 3.79万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=644911
• 关键词: Medical; physics; biomedical; research; increased

The ongoing objective of this research program is to increase the accuracy of dose measurements and dose calculations for any radiation based procedures including, but not limited to, radiation therapy, diagnostic and interventional radiology. This is achieved through a comprehensive research program combining elements of basic and applied research in medical physics and biomedical engineering. The program hinges on radiation physics, optics, numerical optimization problems, image and signal processing and high-performance computing.**Over the next five year, my research program will be based on four main research tracks, namely 1) development of new radiation dosimeters, 2) applied medical image processing, 3)numerical computation in optimization problems and high precision particle transport and dose calculations and 4) robotic medical devices. We will pursue aggressively our optics-based radiation detector research track for which 1 patent has been granted, 4 new provisional patents taken and 1 technology licensed and commercialized in the last 5 years. We have recently shown proof-of-principal for multi-point scintillation fiber dosimeters, a completely new concept in the field. My laboratory is a recognized world leader in optics-based dosimeter developments and the proposed program is intended to maintain and extend this lead.**The proposed research is a highly innovative medical physics and biomedical engineering program. These themes have proven to be extremely productive in term of scientific outputs, patents and HQP training. The proposed program extends the research topics significantly. While the long-term application and commercialization potential are in the medical field (cancer, radiation therapy and radiology), the science discovery and technology development are embedded in a strong science and engineering research program. Our HQP trainees are in high demands. Our program has far reaching impacts: scientific, commercial and ultimately on the quality of life of Canadian through the applications of the said technologies.******

本研究计划的持续目标是提高任何基于辐射的程序（包括但不限于放射治疗、诊断和介入放射学）的剂量测量和剂量计算的准确性。这是通过一个综合的研究计划，结合医学物理学和生物医学工程的基础和应用研究的元素来实现的。该计划涉及辐射物理，光学，数值优化问题，图像和信号处理以及高性能计算。在未来五年，我的研究计划将基于四个主要研究方向，即1）新型辐射剂量计的开发，2）应用医学图像处理，3）优化问题的数值计算和高精度粒子输运和剂量计算以及4）机器人医疗设备。我们将积极推进基于光学的辐射探测器研究，在过去5年中，我们已获得1项专利，4项新的临时专利，1项技术获得许可并商业化。我们最近展示了多点闪烁光纤剂量计的原理证明，这是该领域的一个全新概念。我的实验室在光学剂量计开发方面是公认的世界领先者，拟议的计划旨在保持和扩大这一领先地位。**拟议的研究是一个高度创新的医学物理和生物医学工程计划。事实证明，这些主题在科学产出、专利和HQP培训方面非常富有成效。该计划的提出大大扩展了研究课题。虽然长期的应用和商业化潜力是在医疗领域（癌症，放射治疗和放射学），科学发现和技术开发是嵌入在一个强大的科学和工程研究计划。我们的HQP学员要求很高。我们的计划具有深远的影响：科学，商业，并最终通过上述技术的应用对加拿大的生活质量。