Developing an Economical Synthesis of High-Value Chemical Feedstocks

开发高价值化学原料的经济合成方法

• 批准号: 520228-2017
• 负责人: Murphy, Graham
• 金额: $ 0.91万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Engage Plus Grants Program
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=640173
• 关键词: Developing; Economical; Synthesis; Value; Chemical

Isowater is currently in the research and development phase of expanding their line of isotope-enrichedcompounds. Isowater is currently the only large-scale, worldwide provider of enriched deuterium oxide for theLife Sciences, High Technology and Environmental Science applications (eg. non-nuclear). Customers in someof these applications are requesting deuterated versions of commonly used chemical feedstocks for use innumerous applications, such as in the pharmaceutical and electronics industries.Isowater is currently purchasing their deuterated chemical feedstocks, and converting these into value-addedcommercial compounds. They lack the chemical expertise and facility to develop and evaluate their ownsynthesis of these deuterated chemicals, and also the facility to develop the necessary analytical tools fordetermining the isotopic purity of the compounds synthesized.By continuing their collaboration with the Murphy laboratory, they will gain access to the required personnel,expertise, facilities and equipment necessary to undertake this next step in fundamental research. The Murphylab will use their expertise in chemical synthesis to develop a scaleable and reproducible synthesis of thedeuterated chemical feedstocks, and transfer this new technology to Isowater.

Isowater目前正处于研发阶段，以扩大其富含同位素的化合物产品线。Isowater是目前全球唯一一家为生命科学、高科技和环境科学应用（例如：非核）。其中一些应用的客户要求将常用化学原料的氘化版本用于许多应用，如制药和电子行业。Isowater目前正在购买他们的氘化化学原料，并将其转化为增值的商业化合物。他们缺乏化学专业知识和设备来开发和评估自己合成这些氘代化学品的能力，也缺乏开发必要的分析工具来确定合成化合物的同位素纯度的能力。通过继续与墨菲实验室的合作，他们将获得进行下一步基础研究所需的人员、专业知识、设施和设备。Murphylab将利用他们在化学合成方面的专业知识，开发一种可规模化和可重复的氘代化学原料合成方法，并将这项新技术转让给Iswater。