Acquisition of an Automated High-Throughput Cell Imaging System

购置自动化高通量细胞成像系统

• 批准号: RTI-2018-00813
• 负责人: Maréchal, Alexandre
• 金额: $ 10.93万
• 依托单位: Université de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642163
• 关键词: Acquisition; Automated; Throughput; Cell; Imaging

Live-cell imaging of cellular dynamics has become an essential part of research programs in molecular and cellular biology. Such technology allows scientists to monitor cell fate and gather critical temporally- and spatially-defined phenotypic information in response to virtually any treatment. Until very recently, these experiments were performed on highly expensive high-content imaging systems (often >$500,000) for which data analysis requires specialized dedicated personnel and which can usually only handle a single experiment at once making this technology difficult to access in multi-lab departments.

细胞动力学的活细胞成像已经成为分子和细胞生物学研究计划的重要组成部分。这种技术使科学家能够监测细胞命运，并收集关键的时间和空间定义的表型信息，以应对几乎任何治疗。直到最近，这些实验都是在非常昂贵的高容量成像系统（通常> 50万美元）上进行的，数据分析需要专门的专门人员，并且通常只能同时处理单个实验，使得该技术难以在多实验室部门中使用。