Field Flow Fractionation for Evaluating Colloid-Metal Interactions in Drinking Water

用于评估饮用水中胶体-金属相互作用的场流分级

• 批准号: RTI-2018-00435
• 负责人: Gagnon, Graham
• 金额: $ 10.12万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642287
• 关键词: Field; Flow; Fractionation; Evaluating; Colloid

Field-Flow Fractionation (FFF) will offer Dr. Gagnon’s research team an opportunity to be at the forefront of water treatment design in processes related to corrosion control; biofilm engineering and natural organic matter. Specifically, FFF coupled with inductively coupled plasma mass spectrometry (ICP-MS) will allow the research team to understand colloid-metal particles (i.e., nano-sized particles) in drinking water. Dr. Gagnon’s team has proven track record for utilizing advanced analytical techniques to understand the interaction of colloids and neurotoxic metals, such as lead. With an estimated relative abundance of 40-60% in drinking water, lead in the colloidal fractions represents a significant portion of total lead. Using existing equipment, Dr. Gagnon’s research team can estimate relative abundance and size of colloidal lead in drinking water; however, FFF offers an opportunity to increase precision. In Canada and across many jurisdictions, there is a strong desire to lower regulatory limits for metals such as lead, manganese and aluminum in drinking water. Accordingly, there is a need to distinguish between colloidal-particle and dissolved metals to ensure that proper public health based decisions are made and that water treatment plant design and operation can respond to emerging regulations. The proposed FFF system will accelerate a robust research program that has a combined value of over $5M and will contribute to the training of over 60-HQP over the next five years. Key NSERC-funded research includes the Halifax Water/NSERC Industrial Research Chair, a Collaborative Research and Development Grant and a proposed Discovery Grant. Dr. Gagnon’s team has the necessary research experience and trained personnel to quickly utilize the proposed equipment and integrate across research programs. Particle separation with FFF occurs primarily based on particle size and density, depending on the external force applied. Coupled to a detector, such as ICP-MS, the research team will be able to quantify colloidal metals based on their size and mass. As Dr. Gagnon’s team regularly uses ICP-MS for detecting lead and other metals in drinking water, it is anticipated that start-up with this new instrument will be rapid. Although FFF is widely used in the pharmaceutical and health-care sector, it is rarely used by the drinking water community. Further, we are not aware of similar equipment at Dalhousie University. As such, it is anticipated that the equipment will offer breakthrough information to assist water treatment decision-making, specifically as it relates to corrosion control, biological filtration and particle-separation processes.

场流分馏（FFF）将为Gagnon博士的研究团队提供一个在与腐蚀控制相关的过程中处于水处理设计前沿的机会；生物膜工程与天然有机物。具体来说，FFF与电感耦合等离子体质谱（ICP-MS）相结合将使研究团队能够了解饮用水中的胶体金属颗粒（即纳米级颗粒）。Gagnon博士的团队已经证明了利用先进的分析技术来了解胶体和神经毒性金属（如铅）的相互作用的记录。据估计，饮用水中铅的相对丰度为40-60%，胶体组分中的铅占总铅的很大一部分。利用现有的设备，加格农博士的研究小组可以估计饮用水中胶体铅的相对丰度和大小；但是，FFF提供了提高精度的机会。在加拿大和许多司法管辖区，人们强烈希望降低饮用水中铅、锰和铝等金属的监管限制。因此，有必要区分胶体颗粒和溶解金属，以确保作出适当的基于公共卫生的决定，并确保水处理厂的设计和运营能够对新出台的法规作出反应。拟议的FFF系统将加速一个强大的研究项目，该项目总价值超过500万美元，并将在未来五年内为超过60名hqp的培训做出贡献。NSERC资助的主要研究包括哈利法克斯水/NSERC工业研究主席，合作研究与发展补助金和拟议的发现补助金。Gagnon博士的团队拥有必要的研究经验和训练有素的人员，可以快速利用拟议的设备并整合各个研究项目。与FFF的颗粒分离主要基于颗粒大小和密度，取决于施加的外力。与ICP-MS等探测器相结合，研究团队将能够根据胶体金属的大小和质量对其进行量化。由于Gagnon博士的团队经常使用ICP-MS检测饮用水中的铅和其他金属，预计这种新仪器的启动将很快。虽然FFF广泛用于制药和保健部门，但饮水界很少使用它。此外，我们不知道达尔豪斯大学有类似的设备。因此，预计该设备将提供突破性的信息，以协助水处理决策，特别是与腐蚀控制、生物过滤和颗粒分离过程有关的信息。