Operations and Maintenance Support: Proteomic Resource Center

运营和维护支持：蛋白质组资源中心

• 批准号: RTI-2017-00082
• 负责人: Figeys, Daniel
• 金额: $ 5.95万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642367
• 关键词: Operations; Maintenance; Support; Proteomic; Resource

The Proteomic Resource Center (PRC) provides access to biological mass spectrometry to Canadian scientists with a focus on Eastern Ontario and Quebec. The PRC focuses on quantitive proteomics (large scale analysis of proteins), quantitive lipidomics (large scale analysis of lipids), quantitive metaproteomics (large scale analysis of proteins from bacterial communities) and bioinformatics. The PRC offers technologies to the scientific community that are unique in Canada and some in the world. Requests for access to the PRC have grown two fold in the last five years. The PRC has spearheaded an international effort to enhance access to different mass spectrometers. In particular, it has created a network of facilities from Canada (University of Ottawa and Université Laval) and China (Shanghai and Dalian) greatly enhancing the type and quantity of mass spectrometers, as well as technologies available to the scientific community. This model of access is unique to the PRC. The PRC currently supports over 60 scientific projects from Canadian and international scientists. The types of projects supported by the PRC are broad including: technology development, understanding fundamental biological processes in model organisms such as yeast and zebrafish, and applied projects related to human diseases such as Alzheimer’s Disease, Parkinson Disease, and Inflammatory Bowel Disease in children. The PRC provides extensive training in biological mass spectrometry and bioinformatics. The anticipated outcomes from the PRC are: well-trained young scientists, technologies that can be commercialized, better understanding of fundamental processes important for human health, and tools such as biomarkers, that are directly applicable in the clinic.

蛋白质组学资源中心（PRC）为加拿大科学家提供生物质谱分析，重点是东安大略和魁北克。PRC专注于定量蛋白质组学（大规模蛋白质分析），定量脂质组学（大规模脂质分析），定量元蛋白质组学（大规模细菌群落蛋白质分析）和生物信息学。中国为科学界提供的技术在加拿大和世界上都是独一无二的。在过去五年中，要求进入中华人民共和国的人数增加了两倍。中华人民共和国已率先在国际上努力提高对不同质谱仪的获取。特别是，它建立了一个由加拿大（渥太华大学和拉瓦尔大学）和中国（上海和大连）的设施组成的网络，大大加强了质谱仪的类型和数量以及科学界可用的技术。这种进入模式是中国独有的。中国目前支持来自加拿大和国际科学家的60多个科学项目。中国支持的项目类型广泛，包括：技术开发，了解酵母和斑马鱼等模式生物的基本生物过程，以及与阿尔茨海默病，帕金森病和儿童炎症性肠病等人类疾病相关的应用项目。PRC提供生物质谱和生物信息学方面的广泛培训。中国的预期成果是：训练有素的年轻科学家，可以商业化的技术，更好地了解对人类健康至关重要的基本过程，以及直接适用于临床的生物标志物等工具。