Microfluidics and BioMEMS

工程微系统通过提供能够有效地与生物样品相互作用的工具，并解决用现有技术难以解决的基本/实际问题，在生物/医学方面具有重要的应用。这项研究计划将开发：(1)纸基微流控生物传感器，用于低成本、医疗保健点疾病诊断；(2)用于高通量、基于蠕虫的药物筛选的自动化微流控系统。这种纸基生物传感器将为加拿大医疗保健系统提供低成本的诊断解决方案，并在改善服务不足地区的人类健康方面具有巨大潜力。微流控药物筛选系统将利用微生物进行高通量、高成本效益的药物筛选，并促进制药业的药物发现活动。

Engineering microsystems have important applications in biology/medicine by providing enabling tools to efficiently interact with bio-samples and address fundamental/practical issues difficult to solve with existing techniques. This research program will develop: (1) paper-based microfluidic biosensors for low-cost, point-of-care disease diagnostics; and (2) an automated microfluidic system for high-throughput, worm-based drug screening. The paper-based biosensors will provide low-cost diagnostic solutions for the Canadian healthcare system, and have a significant potential to improve human health in underserved regions. The microfluidic drug screening system will enable high-throughput, cost-effective drug screening using small organisms, and facilitate drug discovery activities in the pharmaceutical industry.