Microfluidics and BioMEMS

微流体和生物MEMS

• 批准号: 1000228836-2012
• 负责人: Liu, Xinyu
• 金额: $ 3.64万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642556
• 关键词: Microfluidics; BioMEMS

Engineering microsystems have important applications in biology/medicine by providing enabling tools to efficiently interact with bio-samples and address fundamental/practical issues difficult to solve with existing techniques. This research program will develop: (1) paper-based microfluidic biosensors for low-cost, point-of-care disease diagnostics; and (2) an automated microfluidic system for high-throughput, worm-based drug screening. The paper-based biosensors will provide low-cost diagnostic solutions for the Canadian healthcare system, and have a significant potential to improve human health in underserved regions. The microfluidic drug screening system will enable high-throughput, cost-effective drug screening using small organisms, and facilitate drug discovery activities in the pharmaceutical industry.

工程微系统通过提供使能工具来有效地与生物样品交互并解决现有技术难以解决的基本/实际问题而在生物学/医学中具有重要的应用。该研究计划将开发：（1）用于低成本，即时疾病诊断的纸基微流体生物传感器;和（2）用于高通量，基于蠕虫的药物筛选的自动微流体系统。纸基生物传感器将为加拿大医疗保健系统提供低成本的诊断解决方案，并具有改善服务不足地区人类健康的巨大潜力。微流控药物筛选系统将使高通量，具有成本效益的药物筛选使用小生物体，并促进药物发现活动在制药行业。