Development of a nanoparticle-based substrate to anchor a pathogen sensing system

开发基于纳米颗粒的基底来锚定病原体传感系统

• 批准号: 536205-2018
• 负责人: Herrera, Jose
• 金额: $ 1.82万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=653487
• 关键词: Development; nanoparticle; based; substrate; anchor

Recent advances on the synthesis and surface modification of nanoparticles have opened the potential to develop rapid-response and highly sensitive pathogen detection systems. However, the wide range properties of the different types of nanoparticles currently available complicate the selection of a suitable nanoparticle substrate for a pathogen sensing system. Genemis Laboratories Inc. specializes in microbiological water testing. However, further development of their proprietary pathogen sensing technology is hindered by the availability of substrates able to anchor pathogen sensing systems that do not interfere with the sensor response. The proposed project aims at narrowing up the options available for a nanoparticle substrate able to host a carbohydrate/chromophore pair able to detect pathogens in water.

纳米粒子的合成和表面修饰的最新进展为开发快速响应和高灵敏度的病原体检测系统开辟了可能性。然而，目前可用的不同类型的纳米颗粒的广泛性质使选择用于病原体感测系统的合适的纳米颗粒基底复杂化。Genemis Laboratories Inc.专门从事水的微生物检测。然而，其专有的病原体感测技术的进一步发展受到能够锚病原体感测系统的基底的可用性的阻碍，所述基底不干扰传感器响应。拟议的项目旨在缩小纳米颗粒基底的选择范围，该基底能够容纳能够检测水中病原体的碳水化合物/发色团对。