课题基金 / 基金详情

Age-dependent development of a primary Tauopathy: the gut/brain axis and biogenesis of Tau strains

Age-dependent development of a primary Tauopathy: the gut/brain axis and biogenesis of Tau strains
原发性 Tau 蛋白病的年龄依赖性发展:肠/脑轴和 Tau 菌株的生物发生
批准号:
398861
负责人:
Westaway David
金额:
$32.78万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-11-01 至 2021-11-01

项目摘要

项目成果

Westaway David的其他基金

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中文摘要
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英文摘要
Diverse diseases appear during aging and some of the more important ones affect the brain. Specifically, chronological age is the most potent risk factor for the common form of Alzheimer's Disease (AD). This form of AD is not caused by inherited mutations
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Diverse disease-associated forms of tau; molecular cell biology and relationships to pathogenesis.
  • 批准号:
    420911
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.37万
  • 财政年份:
    2020
  • 负责人:
    Westaway David
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Molecular switch function in a prion protein; control of pathways leading to pathogenesis or disease remediation
  • 批准号:
    401143
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    Operating Grants
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    $58.52万
  • 财政年份:
    2019
  • 负责人:
    Westaway David
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Visualizing stochastic protein misfolding to understand the origins of sporadic Tauopathies
  • 批准号:
    347409
  • 项目类别:
    Operating Grants
  • 资助金额:
    $17.82万
  • 财政年份:
    2016
  • 负责人:
    Westaway David
  • 依托单位:
Prion Protein Proteostasis
  • 批准号:
    304248
  • 项目类别:
    Operating Grants
  • 资助金额:
    $51.74万
  • 财政年份:
    2014
  • 负责人:
    Westaway David
  • 依托单位: