Molecular switch function in a prion protein; control of pathways leading to pathogenesis or disease remediation
朊病毒蛋白的分子开关功能;
基本信息
- 批准号:401143
- 负责人:
- 金额:$ 58.52万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2019
- 资助国家:加拿大
- 起止时间:2019-03-01 至 2024-03-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Neurodegenerative diseases are an enormous and growing public health concern yet they lack interventions that go beyond symptomatic relief to be mechanism-based. This project will target a) the pathways by which PrP, a cell-surface protein, determines det
神经退行性疾病是一个巨大的和日益增长的公共卫生问题,但他们缺乏超越症状缓解机制的干预措施。该项目将针对a)PrP(一种细胞表面蛋白)决定DET的途径,
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Westaway David其他文献
Westaway David的其他文献
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{{ truncateString('Westaway David', 18)}}的其他基金
Diverse disease-associated forms of tau; molecular cell biology and relationships to pathogenesis.
与疾病相关的多种形式的 tau 蛋白;
- 批准号:
420911 - 财政年份:2020
- 资助金额:
$ 58.52万 - 项目类别:
Operating Grants
Age-dependent development of a primary Tauopathy: the gut/brain axis and biogenesis of Tau strains
原发性 Tau 蛋白病的年龄依赖性发展:肠/脑轴和 Tau 菌株的生物发生
- 批准号:
398861 - 财政年份:2018
- 资助金额:
$ 58.52万 - 项目类别:
Operating Grants
Visualizing stochastic protein misfolding to understand the origins of sporadic Tauopathies
可视化随机蛋白质错误折叠以了解散发性 Tau蛋白病的起源
- 批准号:
347409 - 财政年份:2016
- 资助金额:
$ 58.52万 - 项目类别:
Operating Grants
PrP N-terminal sequences and biological endpoints in Prion and Alzheimer's Disease
PrP N 末端序列和朊病毒和阿尔茨海默病的生物学终点
- 批准号:
255928 - 财政年份:2012
- 资助金额:
$ 58.52万 - 项目类别:
Operating Grants
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