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Diverse disease-associated forms of tau; molecular cell biology and relationships to pathogenesis.

Diverse disease-associated forms of tau; molecular cell biology and relationships to pathogenesis.
与疾病相关的多种形式的 tau 蛋白;
批准号:
420911
负责人:
Westaway David
金额:
$64.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-03-01 至 2025-03-01

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中文摘要
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英文摘要
Lay summary. The well-known brain deposits in Alzheimer's Disease (AD) called neurofibrillary tangles (NFT) are made of a protein called tau, while the other hallmark of AD, the plaques, are made of a different, shorter protein molecule called Abeta. Whil
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Molecular switch function in a prion protein; control of pathways leading to pathogenesis or disease remediation
  • 批准号:
    401143
  • 项目类别:
    Operating Grants
  • 资助金额:
    $58.52万
  • 财政年份:
    2019
  • 负责人:
    Westaway David
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Age-dependent development of a primary Tauopathy: the gut/brain axis and biogenesis of Tau strains
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    398861
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    Operating Grants
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    $32.78万
  • 财政年份:
    2018
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    Westaway David
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Visualizing stochastic protein misfolding to understand the origins of sporadic Tauopathies
  • 批准号:
    347409
  • 项目类别:
    Operating Grants
  • 资助金额:
    $17.82万
  • 财政年份:
    2016
  • 负责人:
    Westaway David
  • 依托单位:
Prion Protein Proteostasis
  • 批准号:
    304248
  • 项目类别:
    Operating Grants
  • 资助金额:
    $51.74万
  • 财政年份:
    2014
  • 负责人:
    Westaway David
  • 依托单位:
海外基金