New tools for Varroa mite management in beekeeping

养蜂业瓦螨管理新工具

基本信息

  • 批准号:
    494068-2016
  • 负责人:
  • 金额:
    $ 9.22万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Strategic Projects - Group
  • 财政年份:
    2018
  • 资助国家:
    加拿大
  • 起止时间:
    2018-01-01 至 2019-12-31
  • 项目状态:
    已结题

项目摘要

Honey bees are among the most important ecological service providers in modern agricultural landscapes: they are responsible for approximately 90% of pollination needed to produce seeds and/or high quality fruit and produce. Due to intensification of beekeeping and agriculture, bees suffer from deadly parasites and diseases that can lead to sudden collapse of bee colonies. Varroa destructor, a honey bee-specific external parasitic mite, is among the most serious disease agents of honey bees, because the mites transmit crippling viral diseases to bees. These mites reproduce within bee brood cells, and the offspring emerge with the new bees. These adult mites then parasitize adult worker bees until they find new bee brood for their reproduction. The adult mites selectively infect 'nurse' bees - bees that care for the developing offspring - thereby ensuring that they have access to the upcoming generation of bees. Mites detect their adult hosts and the brood by their unique chemical signatures.**We propose to test chemicals that change the host selection of the mites, from nurse bee to another type of worker bee, the 'forager', and/or paralyze the mites and thereby increase their mortality. We discovered these chemicals in experiments that tested the ability of mites to choose between a freshly killed nurse and forager bee, based on the bee odors, and in which the responses of the mite to bee odors and our chemicals were tested. Here we propose tests in cages with live bees and, in years 2 and 3, field tests with the most active chemicals in small colonies. We also will search for the target site of the active chemicals we find. Beekeepers are hungry for new mite control agents to use in sustainable, integrated management programs, because previously used mite control agents are no longer effective, and there are few replacements.******
蜜蜂是现代农业景观中最重要的生态服务提供者之一:它们负责生产种子和/或高质量水果和农产品所需的约90%的授粉。由于养蜂和农业的集约化,蜜蜂遭受致命的寄生虫和疾病,可能导致蜂群突然崩溃。狄斯瓦螨是一种蜜蜂特有的外部寄生螨,是蜜蜂最严重的病原体之一,因为螨将严重的病毒性疾病传播给蜜蜂。这些螨在蜜蜂的巢室中繁殖,后代与新的蜜蜂一起出现。这些成年螨然后寄生成年工蜂,直到他们找到新的蜜蜂繁殖。成年螨选择性地感染“护士”蜜蜂-照顾发育中的后代的蜜蜂-从而确保它们能够接触到下一代蜜蜂。螨通过其独特的化学特征来检测其成年宿主和幼仔。我们建议测试化学品,改变主机选择的螨,从护士蜜蜂到另一种类型的工蜂,“觅食”,和/或麻痹螨,从而增加他们的死亡率。我们在实验中发现了这些化学物质,这些实验测试了螨虫根据蜜蜂气味在刚杀死的护士和觅食蜜蜂之间进行选择的能力,并测试了螨虫对蜜蜂气味和我们的化学物质的反应。在这里,我们建议在笼子里用活蜜蜂进行测试,在第2年和第3年,在小殖民地用最活跃的化学物质进行实地测试。我们还将寻找我们发现的活性化学物质的靶点。养蜂人渴望在可持续的综合管理计划中使用新的螨控制剂,因为以前使用的螨控制剂不再有效,而且很少有替代品。

项目成果

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Plettner, Erika其他文献

Ligand-interaction Kinetics of the Pheromone-Binding Protein from the Gypsy Moth, L. dispar: Insights into the Mechanism of Binding and Release
  • DOI:
    10.1016/j.chembiol.2009.01.005
  • 发表时间:
    2009-02-27
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Gong, Yongmei;Pace, Tamara C. S.;Plettner, Erika
  • 通讯作者:
    Plettner, Erika
Seasonal variation in the titers and biosynthesis of the primer pheromone ethyl oleate in honey bees
  • DOI:
    10.1016/j.jinsphys.2012.05.010
  • 发表时间:
    2012-08-01
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    Castillo, Carlos;Maisonnasse, Alban;Plettner, Erika
  • 通讯作者:
    Plettner, Erika
Identification of Camphor Oxidation and Reduction Products in Pseudomonas putida: New Activity of the Cytochrome P450cam System
  • DOI:
    10.1007/s10886-011-9959-7
  • 发表时间:
    2011-06-01
  • 期刊:
  • 影响因子:
    2.3
  • 作者:
    Prasad, Brinda;Rojubally, Adina;Plettner, Erika
  • 通讯作者:
    Plettner, Erika
Effects of Aromatic Compounds on Antennal Responses and on the Pheromone-Binding Proteins of the Gypsy Moth (Lymantria dispar)
  • DOI:
    10.1093/chemse/bjq130
  • 发表时间:
    2011-03-01
  • 期刊:
  • 影响因子:
    3.5
  • 作者:
    Gong, Yongmei;Plettner, Erika
  • 通讯作者:
    Plettner, Erika
Synthesis of substituted alkoxy benzene minilibraries, for the discovery of new insect olfaction or gustation inhibitors
  • DOI:
    10.1021/cc700139y
  • 发表时间:
    2008-01-01
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Paduraru, Peggy A.;Popoff, Richard T. W.;Plettner, Erika
  • 通讯作者:
    Plettner, Erika

Plettner, Erika的其他文献

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{{ truncateString('Plettner, Erika', 18)}}的其他基金

Structure-Function of Insect Odorant-Binding Proteins and a Bacterial Cytochrome P450: Discovery of Mechanisms and Applications
昆虫气味结合蛋白和细菌细胞色素 P450 的结构功能:机制的发现和应用
  • 批准号:
    RGPIN-2020-05297
  • 财政年份:
    2022
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Individual
Structure-Function of Insect Odorant-Binding Proteins and a Bacterial Cytochrome P450: Discovery of Mechanisms and Applications
昆虫气味结合蛋白和细菌细胞色素 P450 的结构功能:机制的发现和应用
  • 批准号:
    RGPIN-2020-05297
  • 财政年份:
    2021
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Individual
Field trial and prototype optimization of a new agent against the varroa mite, a parasite of honey bees
针对蜜蜂寄生虫瓦螨的新药剂的现场试验和原型优化
  • 批准号:
    548812-2020
  • 财政年份:
    2020
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Idea to Innovation
Structure-Function of Insect Odorant-Binding Proteins and a Bacterial Cytochrome P450: Discovery of Mechanisms and Applications
昆虫气味结合蛋白和细菌细胞色素 P450 的结构功能:机制的发现和应用
  • 批准号:
    RGPIN-2020-05297
  • 财政年份:
    2020
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Individual
Mechanisms of Insect Pheromone-Binding Proteins and a Bacterial Cytochrome P450: Elucidation of Function and New Applications
昆虫信息素结合蛋白和细菌细胞色素 P450 的机制:功能阐明和新应用
  • 批准号:
    RGPIN-2015-06088
  • 财政年份:
    2019
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Individual
Mechanisms of Insect Pheromone-Binding Proteins and a Bacterial Cytochrome P450: Elucidation of Function and New Applications
昆虫信息素结合蛋白和细菌细胞色素 P450 的机制:功能阐明和新应用
  • 批准号:
    RGPIN-2015-06088
  • 财政年份:
    2018
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Individual
New tools for Varroa mite management in beekeeping
养蜂业瓦螨管理新工具
  • 批准号:
    494068-2016
  • 财政年份:
    2017
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Strategic Projects - Group
High Sensitivity Gas Chromatograph Mass Spectrometer
高灵敏度气相色谱质谱仪
  • 批准号:
    RTI-2018-00409
  • 财政年份:
    2017
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Research Tools and Instruments
Mechanisms of Insect Pheromone-Binding Proteins and a Bacterial Cytochrome P450: Elucidation of Function and New Applications
昆虫信息素结合蛋白和细菌细胞色素 P450 的机制:功能阐明和新应用
  • 批准号:
    477793-2015
  • 财政年份:
    2017
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Accelerator Supplements
Mechanisms of Insect Pheromone-Binding Proteins and a Bacterial Cytochrome P450: Elucidation of Function and New Applications
昆虫信息素结合蛋白和细菌细胞色素 P450 的机制:功能阐明和新应用
  • 批准号:
    RGPIN-2015-06088
  • 财政年份:
    2017
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Discovery Grants Program - Individual

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