Liquid-phase electron microscopy for probing dynamic process

用于探测动态过程的液相电子显微镜

• 批准号: 543949-2019
• 负责人: Howe, Jane
• 金额: $ 2.6万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=686494
• 关键词: Liquid; phase; electron; microscopy; probing

Seeing is believing. For hundreds of years, human beings have been on a continuous quest of new technologies that expands our visions to see things either too far away or too small to resolve. Light microscopes, invented in the 1500's, allowed observation of subjects down to sub-micrometer length scales. Electron microscopes, first constructed in 1931, using electrons to probe an object, have since advanced to be able to measure physical, chemical and microstructural information down to the atomic-level. Electron microscopy is conventionally carried out in high vacuum such that only the electron beam interacts with sample. Yet a fast-growing range of scientific research is interested in structure and dynamic processes of materials immersed in liquid at the nanometer length scale, with the option of adding additional stimuli such as heating, electrical current, or light illumination. This project aims to develop and optimize novel technologies for carrying out liquid-phase electron microscopy and correlative microscopy studies in scanning electron microscope (SEM). In order to study materials immersed in liquid, a robust, electronically-transparent liquid-cell is required for containing the specimen and it must integrate well with the operation and data collection of the SEM. We will also build a cryo SEM stage, which can lower the vapor pressure of the liquid. The proposed work will be carried out using the state-of-the art electron microscopy characterization tools at the Ontario Centre for the Characterisation of Advanced Materials at the University of Toronto.University of Toronto will collaborate with Hitachi High Technologies Canada Inc., a Toronto-based instruments distributor and manufacturer, and Norcada Inc., a MEMS technology company located in Edmonton, Alberta, for this project. This research will provide training for 2 graduate students and 2 undergraduate students. It will make a significant contribution to the development and commercialization of high valued-added technologies and products in Canada.

百闻不如一见。数百年来，人类一直在不断地探索新技术，这种技术可以扩大我们的视野，看到或太远或太小而无法解决的事情。S在1500年发明了光学显微镜，可以观察到亚微米长的对象。电子显微镜最早建造于1931年，使用电子来探测物体，自那以后，电子显微镜已经能够测量物理、化学和微观结构信息，精确到原子级别。电子显微镜通常是在高真空中进行的，因此只有电子束与样品相互作用。然而，越来越多的科学研究对浸入纳米尺度液体中的材料的结构和动态过程感兴趣，可以选择添加额外的刺激，如加热、电流或光照明。本项目旨在开发和优化在扫描电子显微镜(SEM)中进行液相电子显微镜和相关显微研究的新技术。为了研究浸入液体中的材料，需要一个坚固的、电子透明的液晶盒来容纳样品，它必须与扫描电子显微镜的操作和数据收集很好地结合在一起。我们还将建造一个低温扫描电子显微镜工作台，它可以降低液体的蒸气压。这项拟议的工作将使用多伦多大学安大略省先进材料表征中心最先进的电子显微镜表征工具进行。多伦多大学将与多伦多仪器分销商和制造商日立高技术加拿大公司以及位于艾伯塔省埃德蒙顿的MEMS技术公司Norcada Inc.合作开展这一项目。本研究将为2名研究生和2名本科生提供培训。它将为加拿大高附加值技术和产品的开发和商业化做出重大贡献。