Innovative biomechanical modelling of the spine with a focus on paraspinal musculature

人体脊柱周围的肌肉在其保持直立姿势的能力中起着重要作用，同时使躯干能够运动。有脊柱的计算机模型可以帮助我们了解这些肌肉的功能，但这些模型使用起来很麻烦。在过去的几年里，我们已经开发了一个人体脊柱模型，该模型使用了加拿大温哥华的不列颠哥伦比亚省（UBC）大学开发的ArtiSynth软件。该软件使用非常高效的算法，求解时间为几分钟而不是几天。该项目的重点是增强人体脊柱的生物力学建模，特别强调椎旁肌肉几何形状和特性的基本作用。这项研究将涉及先进的胸腰椎肌肉骨骼动态模型，手术前后人体脊柱和椎旁肌肉组织的图像分析，以及手术时从受试者身上采集的组织标本的肌肉特性测量。这项研究的长期目标是开发一种针对受试者的，术前计划软件包，可准确预测沿整个胸腰椎沿着的脊柱负荷。

The muscles around the human spine play a fundamental role in its ability to maintain an erect posture while enabling movement of the trunk. There exist computer models of the spine to help us understand the functioning of these muscles, yet these models are cumbersome to use. Over the past several years, we have developed a model of the human spine that uses the ArtiSynth software developed at the University of British Columbia (UBC) in Vancouver, Canada. This software uses a very efficient algorithm such that solution times are on the order of minutes rather than days.The focus of this project is the enhanced biomechanical modelling of the human spine with particular emphasis on the fundamental role of paraspinal muscle geometry and properties. The research will involve advanced musculoskeletal dynamic modelling of the thoracolumbar spine, image analysis of the spine and paraspinal musculature in human subjects pre and post-surgery, and measurement of muscle properties from tissue specimens taken from subjects at the time of surgery.The long-term objective of this research is to develop a subject specific, pre-operative planning software package that would accurately predict spinal loading along the entire thoracolumbar spine.